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Thyroid Information

Posted By: MaxaLisa

Thyroid Information - 03/20/10 11:02 AM

This thread contains the following posts


Thyroid/General Information and Testing
http://www.germanshepherdhome.net/forum/ubbthreads.php?ubb=showflat&Number=21987#Post21987


Thyroid/Seizures
http://www.germanshepherdhome.net/forum/ubbthreads.php?ubb=showflat&Number=21988#Post21988


Thyroid/Behaviour
http://www.germanshepherdhome.net/forum/ubbthreads.php?ubb=showflat&Number=33032#Post33032


Thyroid/Nutrients & Supplements & Drugs
http://germanshepherdhome.net/forum/ubbthreads.php/topics/122237.html#Post122237
Posted By: MaxaLisa

Re: Thyroid/General Information - 03/20/10 11:03 AM

Overviews: Hypothyroidism in Dogs
http://www.vet.uga.edu/VPP/clerk/bell/index.php (UofGA)
http://www.veterinarypartner.com/Content.plx?A=461 (VIN)
http://www.lbah.com/canine/hypot4.htm (Long Beach Animal Hospital)


Possible Symptoms of Hypothyroidism
http://www.siriusdog.com/hypothyroid-dog-signs.htm
http://www.canine-epilepsy-guardian-angels.com/clinicalsignscaninehypothyroidism.htm (same list, different format)


Frequently-Asked Questions: Thyroid Function in Dogs (MSU)
http://animalhealth.msu.edu/Sections/Endocrinology/Thyroid_Canine.php#05


Antech Newsletters on Thyroid
http://www.canine-epilepsy-guardian-angels.com/AntechThyroid.htm
http://web.archive.org/web/2008011801293...02/nov02_01.htm (3 pages)


Thyroid Disease and Autoimmune Thyroiditis
http://www.homevet.com/petcare/Dodds%20on%20thyroid.pdf
http://www.canine-epilepsy-guardian-angels.com/ThyroidDisease.htm


Other FAQs which include some environmental and nutritional factors:
http://www.mirage-samoyeds.com/thyroid3.htm
http://www.ithyroid.com/hypothyroidism_theory.htm
http://jstevens.wordpress.com/2007/09/22/part-2-treating-hypothyroidism-important-nutrients/
http://jstevens.wordpress.com/2007/07/15/treating-my-thyroid-and-adrenals-a-little-about-nutrition/

http://www.drwells.net/nutrition/topics/Hypothyroid.htm
http://drhedberg.com/2011/02/08/the-thyroid-and-thyroid-hormones/

Thyroid Study in Welsh Springer Spaniels
http://www.artwork.net/cok13/thyroid_study.htm#Autoimmune%20Mediated%20Thyroid%20Disease
A study showing that TgAA (a marker for autoimmune thyroiditis) can rise at a very young age (possibly earlier than a year) with rapid destruction of the thyroid. Enough of the thyroid was destroyed so that by 3 1/2 years old the TgAA had returned to normal, which would then show no more evidence of thyroiditis. It was only at this time that the T4 levels (the only thing that many vets test), began to decline. It can take years for thyroid disease to show on standard testing. Other evidence has shown that the thyroid blood tests don't show dysfunction until at least 70% of thyroid is destructed.


Thyroid Testing

(Hemopet/Jean Dodds, Mini lecture by Jean Dodds plays when page is opened, very interesting)
http://www.hemopet.org/services.html

Other Hemopet Info
http://www.canine-epilepsy-guardian-angels.com/DrDoddsInstructions.htm
http://www.canine-epilepsy-guardian-angels.com/DrDoddsInfoForm.htm
Posted By: MaxaLisa

Re: Thyroid/Seizures - 03/20/10 11:05 AM

The Low Thyroid Seizure Connection
http://www.canine-epilepsy.com/Lowthyroid.html


Thyroid and Seizure Disorders
http://www.canine-epilepsy-guardian-angels.com/InterviewDrDoddsAndJoanneCarson.htm


Hashimoto's Encephalopathy, A Neuroendocrine Disorder
http://www.thyroid-info.com/articles/hashimotos-encephalopathy.htm

More:
http://www.lbah.com/word/seizures-epilepsy/
http://dogaware.com/articles/wdjhypothyroid.html
Posted By: MaxaLisa

Re: Thyroid/Behaviour - 04/17/10 06:35 AM

Hyperactivity and the thyroid (excerpt from Dodman):
http://www.randomhouse.com/catalog/display.pperl?isbn=9780553379686&view=excerpt
One other cause of hyperactivity is metabolic dysfunction. Both hypo- and hyperthyroidism can lead to hyperactivity. Hyperthyroidism is extremely rare in dogs but can result from thyroid tumors. Hypothyroidism, on the other hand, is extremely common, and recent evidence suggests that borderline-to-low thyroid function may cause a paradoxical syndrome of increased anxiety, fearfulness, and hyperactivity. The fact that thyroid hormone receptors are affected in some cases of medical hyperactivity (ADHD) provides a fascinating link between these conditions that is worthy of further investigation. Details of the paradoxical hypothyroid syndrome are dealt with in a later section ("V--Veterinary Causes of Behavior Problems").


Assessment of Hypothyroidism as a Factor in Behavior Problems (Dodman)
http://www.petplace.com/article-printer-friendly.aspx?id=5221


Behavioral Changes Associated with Thyroid Dysfunction in Dogs
http://doglinks.co.nz/health/aggr_theroid.htm


Dodman on Thyroid and Behaviour (excerpt from the Well Adjusted Dog)
http://books.google.com/books?id=5f8aABa...;q=&f=false
(starts on page 191, 192, 193)

Behavioral Issues with Thyroiditis
http://www.itsfortheanimals.com/DODDS-BEHV-THYROID.HTM


BEHAVIORAL CHANGES ASSOCIATED WITH THYROID DYSFUNCTION IN DOGS
http://www.canine-epilepsy-guardian-angels.com/behaviorandthyroid.htm


THYROID and its effects on AGGRESSIVE or FEARFUL BEHAVIOR
http://www.diamondsintheruff.com/healthandbehavior.html


Thyroid Can Alter Behavior
http://www.canine-epilepsy-guardian-angels.com/bizarre_behavior.htm


Thyroid Dysfunction as a Cause of Aggression in Dogs and Cats
http://www.doganswers.com/Thyroid.htm


Hypothyroidism and aberrant behaviours in the Bearded Collie
http://www.animalfriend.co.uk/PDF/Hypoth...ed%20Collie.pdf


Serum total thyroxine and thyroid stimulating hormone concentrations in dogs with behavior problems
http://www.journalvetbehavior.com/article/S1558-7878%2809%2900130-0/abstract
The aim of this case controlled study was to determine whether dogs with behavioral problems have evidence of abnormal thyroid function on routine screening tests for hypothyroidism. The hypothesis of the study was that thyroid function, as assessed by serum total thyroxine (TT4) and serum thyroid stimulating hormone (thyrotropin) (TSH) concentrations, is normal in most dogs with behavioral problems. Concentrations of TT4 and TSH in 39 dogs with behavior problems presenting to a veterinary behavior referral clinic (abnormal behavior group), were compared with TT4 and TSH concentrations in 39 healthy control dogs without behavior problems presenting to 5 community veterinary practices (control group). Dogs in the control group were matched for age and breed with the abnormal behavior group. Dogs with behavioral problems had higher TT4 concentrations than dogs without behavioral problems (t-test: t = 2.77, N = 39, P = 0.009), however none of the TT4 values were outside the reference range. There was no significant difference in TSH concentration between the 2 groups. Two dogs with behavior problems and 1 dog without behavior problems had results suggestive of hypothyroidism. All other dogs were considered to be euthyroid. There was no evidence to support a diagnosis of hypothyroidism in the majority of dogs with behavior problems in this study. The higher concentration of TT4 in dogs with behavior problems suggests, however, that alteration in thyroid hormone production or metabolism may occur in some dogs with behavior problems. Further studies that include additional indicators of thyroid status such as serum total triiodothyronine, serum, free thyroxine, and anti-thyroid antibody concentrations are necessary to further evaluate the significance of this finding.
Posted By: MaxaLisa

Re: Thyroid/FurtherImplications of Thyroid Disease - 12/01/10 12:01 AM

A case of primary hypothyroidism causing central nervous system atherosclerosis in a dog
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2465784/

Neuromuscular abnormalities associated with hypothyroidism and lymphocytic thyroiditis
http://www.ncbi.nlm.nih.gov/pubmed/35580...A&linkpos=3
Posted By: MaxaLisa

Re: Thyroid Info/Nutrients, Supplements, & Drugs - 01/09/11 11:04 PM

On adequate thyroxine replacement and still symptomatic

Endocrine Abstracts (2009) 19 P90
MS Kamaruddin & SH Pearce
Royal Victoria Infirmary,
Newcastle Upon Tyne, UK.

Hypothyroid patients often present with non-specific symptoms and some of these may persist despite adequate thyroxine replacement, including weakness, poor memory, paraesthesia and numbness or coldness of the extremities.

In patients on thyroxine who have been referred due to persistent symptoms, we routinely look for vitamin B12 deficiency, if symptoms persist once thyroxine replacement has been optimised.

We present three patients who remained symptomatic despite adequate thyroxine replacement. Patient A and B described joint pains with mood swings. Patient C however described symptoms of poor balance and poor concentration. All of them had markedly subnormal plasma B12 levels, which were confirmed before treatment with intramuscular hydroxycobalamin. Surrogate markers including antibodies and macrocytosis were negative in all three cases. All had significant improvement in their symptoms.

http://www.endocrine-abstracts.org/ea/0019/ea0019p90.htm


Drugs that might interfere with thyroid function

Cipro (take 6 hrs apart):

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC557149/
http://www.bmj.com/content/330/7498/1002.1.full
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