Hollywood Brand Safflower Oil
The ingredient that is said to be beneficial here is linoleic acid. There are two major brands of safflower oil on the market: Hain and Hollywood. Apparently Hollywood is the brand with the most linoleic acid and is the brand of choice in this somewhat controversial treatment. In one study using eight dogs with Mycosis fungoides (the skin T-cell form of lymphoma), six dogs achieved remission with no other therapy.
In 1999, at the annual American College of Veterinary Dermatology meeting, two case reports were presented: one dog out of remission for mycosis fungoides after chemotherapy, and the other having had no other therapy for mycosis fungoides. The first dog had a partial response to the safflower oil and the other achieved prolonged remission.
Minimal adverse effects come with the use of this oil (if too much oil is used there is a possibility of pancreatitis but, in general, obesity from the fat is the only problem). Safflower oil is inexpensive and readily available.
So what is the catch? Should all lymphoma patients be on this oil? Safflower oil is an omega 6 fatty acid. Omega 6 fatty acids have been shown in other studies to have properties that actually support cancer growth. At this point, safflower oil seems to be a reasonable option only for mycosis fungoides and not other forms of lymphoma.
Effect of fish oil, arginine, and doxorubicin chemotherapy on remission and survival time for dogs with lymphoma: a double-blind, randomized placebo-controlled study.
Cancer 88:1916-28 2000 Apr 15
Ogilvie GK, Fettman MJ, Mallinckrodt CH, Walton JA, Hansen RA, Davenport DJ, Gross KL, Richardson KL, Rogers Q, Hand MS
Cancer Lett 1992 May 30;64(1):17-22
Linoleate produces remission in canine mycosis fungoides.
Iwamoto KS, Bennett LR, Norman A, Villalobos AE, Hutson CA
Department of Radiological Sciences, University of California, Los Angeles 90024.
The Use of Safflower Oil for the Treatment of Mycosis Fungoides in Two Dogs.
Peterson, A., Wood, S., and Rosser, E. Dept of Small Animal Clinical Sciences, D208 Veterinary Medical Center, Michigan State University, East Lansing, MI.http://www.veterinarypartner.com/Content.plx?P=PRINT&A=1697