http://haileybell.homestead.com/Supplements.html

The supplement program give there, Haley was a 60 lb Dolberman:

"Following supplements were given each day with each specific meal (Hailey ate four to five times a day):

Batch #1:
(2) IP-6 Celle Forte(220mg.), (1) Swiss Formula Anti-Oxidant capsule (contains 10,000IU Beta-Carotene / 500mg Vit. C / 25mcg. Selenium), (3) Reishi Mushroom capsules(1000mg each), (3) Maitake Mushroom caps(800mg each), (3) Shiitake Mushroom caps(800mg each), (2) Ester Vitamin C(600mg each), (3) Prednisone, every other day(5mg each)

Batch #2:
(2) IP-6, (1) Co-Enzyme Co-Q10(30mg), 1 ounce Flor-Essence diluted with 2 ounces water (or Essiac Tea is acceptable), (1) Green Tea capsule(50mg), (2) Salmon Oil**(1000mg each), 2 teaspoons Greens+ powder

Batch #3:
(2) IP-6, (1) high quality human grade IRON FREE Multi Vitamin, (2) Shark Cartilige, (2) Ester Vitamin C, (3) Reishi Mushroom caps, (2) Cat's Claw(670mg each), (2) Grape Seed extract capsules, (2) Moducare Sterinol tablets, (1) Salmon Oil cap**

Batch #4:
(3) Maitake Mushroom caps, (3) Shiitake Mushroom caps, 2 teaspoons Wheatgrass powder, 2 tablespoons Flax Seed Oil**

Batch #5:
(2) IP-6, (1) Selenium(100mcg), (1) Co-Enzyme Q-10, (1) Ester Vitamin C, 1 ounce Flor-Essence(diluted with 2 ounces water)

Liver Supplements & Medications:

*A mistake of administering Lomustine/CCNU & Methotrexate (chemotherapy drugs) within too short a time frame led to severe liver damage for Hailey in April of 2001. Thankfully, a combination of supplements and medications has pulled her through what should have been a potentially terminal condition. Had I researched the hepatic toxicity of certain chemo drugs more thoroughly, I would have started Hailey on her liver supplements when we started her first chemotherapy protocol. *It is important to note that Hailey no longer receives Vitamin C or Garlic (liver related issues)

Liver Supplements (given twice daily):
Turmeric - 1000mg
Artichoke Leaves Extract - 1800mg
Dandelion Extract - 1500mg
SAMe - 200 mg (started in 2003)
Milk Thistle - 3000mg (<--- very important liver supplement, with SAMe being a close second)

Liver Medications:
Ursodiol (Actigal) 250mg (once a day)
Penicillamine 250mg / 2 times a day (500mg total per day)

Anti-angiogenic medication:
Doxycycline 50mg / 3 times a day (150mg total per day): Doxy helps to prevent cancer spread and blood vessel growth around tumors and seems to be effective with osteosarcoma cases. Doxy appears to be beneficial for lymphoma cancers as well (with Hailey being the evidence of this)

We try to give some of the above supplements between meals, especially IP-6. The more "spread out" the supplements are throughout the day and evening, the better.
**Stop excessive fatty acid/fish oil supplementation 2-3 days prior to any chemo, until 2 days after."

Hollywood Brand Safflower Oil

The ingredient that is said to be beneficial here is linoleic acid. There are two major brands of safflower oil on the market: Hain and Hollywood. Apparently Hollywood is the brand with the most linoleic acid and is the brand of choice in this somewhat controversial treatment. In one study using eight dogs with Mycosis fungoides (the skin T-cell form of lymphoma), six dogs achieved remission with no other therapy.

In 1999, at the annual American College of Veterinary Dermatology meeting, two case reports were presented: one dog out of remission for mycosis fungoides after chemotherapy, and the other having had no other therapy for mycosis fungoides. The first dog had a partial response to the safflower oil and the other achieved prolonged remission.

Minimal adverse effects come with the use of this oil (if too much oil is used there is a possibility of pancreatitis but, in general, obesity from the fat is the only problem). Safflower oil is inexpensive and readily available.

So what is the catch? Should all lymphoma patients be on this oil? Safflower oil is an omega 6 fatty acid. Omega 6 fatty acids have been shown in other studies to have properties that actually support cancer growth. At this point, safflower oil seems to be a reasonable option only for mycosis fungoides and not other forms of lymphoma.

References


Effect of fish oil, arginine, and doxorubicin chemotherapy on remission and survival time for dogs with lymphoma: a double-blind, randomized placebo-controlled study.
Cancer 88[8]:1916-28 2000 Apr 15

Ogilvie GK, Fettman MJ, Mallinckrodt CH, Walton JA, Hansen RA, Davenport DJ, Gross KL, Richardson KL, Rogers Q, Hand MS
Cancer Lett 1992 May 30;64(1):17-22
Linoleate produces remission in canine mycosis fungoides.
Iwamoto KS, Bennett LR, Norman A, Villalobos AE, Hutson CA
Department of Radiological Sciences, University of California, Los Angeles 90024.

The Use of Safflower Oil for the Treatment of Mycosis Fungoides in Two Dogs.
Peterson, A., Wood, S., and Rosser, E. Dept of Small Animal Clinical Sciences, D208 Veterinary Medical Center, Michigan State University, East Lansing, MI.

http://www.veterinarypartner.com/Content.plx?P=PRINT&A=1697